Ebola aka Ebola virus (EBOV), is a viral genus, first emerged in 1976 in Zaire, causing Ebola hemorrhagic fever. There are 4 known species carrying the Ebolavirus genus,The ”Zaire virus” is the first discovered and the most fatal. The virus obstructs with the endothelial cells, in the internal surface of blood vessels,damaging the blood vessels walls. Ebola spreads through the body fluids fluids and skin.Ebola.
Researchers state that the rates of genetics variations are one hundred times slower than influenza type A in human, though keeping similar degree as those of hepatitis B. Extrapolating backwards specify that Ebola virus and Marburg virus deviate many years before.
Ebola has 5 classes such as:
ZEBOV – Zaire Ebolavirus
CIEBOV – Côte d’Ivoire Ebolavirus
SEBOV – Sudan Ebolavirus
REBOV – Reston Ebolavirus
BEBOV – Bundibugyo Ebolavirus
There are different symptoms for Ebola, its incubation period extends from two to twenty one days, and they are as follow:
1.High fever (38.5 approximately) accompanied with headache, body pain,sore throat and general weakness.
2. Ebola patient would feel, dizziness, internal and external bleeding. At early stage, these symptoms could be mistaken for Malaria or dysentery or typhoid or other bacterial infections
3. In case suffering Ebola, other symptoms will rise, as patient will experience diarrhea, bloody feces and vomiting, in addition to red eyes and hemoragy.
4. Other symptoms include low blood pressure and tachycardia. Interior bleeding occurs due to reaction between the virus and blood platelets leading to holes formation in the capillary walls.
5. Eyes swelling, ears, nose and mouth internal and external hemorrhage. In addition to rash all over the body.
Ebola hemorrhagic fever is caused by a virus originated to Filoviridae family. Ebola includes 5 sorts of virus, which 4 of them is causing disease:ZEBOV (Zaire Ebolavirus), CIEBOV (Côte d’Ivoire Ebolavirus), REBOV (Reston Ebolavirus), SEBOV (Sudan Ebolavirus), BEBOV (Bundibugyo Ebolavirus)
The disease is transmitted from infected animal and could be transmitted from a person to another through close contact, fluids or infected medical equipments
So far, there is no recognized treatment, as antiviral are not effective against the Ebola virus.
The patient kept in the hospital under intensive care. Other are taken such as, intravenous medications.
Incase of bleeding, transfusion of fresh blood is required.
Ebola Virus is identical clinically with Marbug virus, yet can also simply be mystified with other viral hemorrhagic fevers, such as,Typhoid Fever,Shigelosis and Malaria in addition to Cholera, Borreliosis and Typhus.
There are other contagious diseases included in the differential diagnosis such as small pox, Q fever, measles, Plague and viral Hepatitis.
Patient’s history is the main indicator for Ebola Virus infection, particularly previous travels and profession. Ebola virus disease infection could be confirmed through the Ebla virus isolation and by detection of Ebola virus antigen in patient blood sample during the acute phase of Ebola virus disease. This can be detected and identified easily by the electronic microscope. Electronic microscope could not distinguish the various filoviruses no matter how the long it is.
During an outbreak, virus isolation and electron microscopy are usually not feasible options. The most common diagnostic methods are RT-PCPR in addition to ELISA which can be done in field or mobile labs and hospitals.